MethylGene and Pharmion present favorable clinical data from combination MGCD0103/Vidaza® study

MethylGene and Pharmion present favorable clinical data from combination MGCD0103/Vidaza® study

MethylGene Inc. (TSX:MYG) and Pharmion Corporation (Nasdaq: PHRM) today announced maturing data from the Phase I/II study investigating the combined use of MGCD0103, a novel, isotype-selective histone deacetylase (HDAC) inhibitor, and Vidaza® (azacitidine for injection) in patients with myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML). A 53 percent response rate (n=19) was demonstrated at the 90 mg dose with a median time to response of less than two months. The overall results indicate a 36 percent response rate for patients evaluated at all doses (n=52 evaluable patients) in this Phase I/II study. The data were presented in an oral presentation today at the 49th Annual Meeting and Exposition of the American Society of Hematology (ASH) in Atlanta.

MethylGene and Pharmion report favorable results for Phase 2 single-agent studies in relapsed or refractory lymphomas

MethylGene Inc. (TSX:MYG) and Pharmion Corporation (Nasdaq: PHRM) today announced preliminary data from two ongoing Phase II studies with MGCD0103, the Companies' novel, isotype- selective histone deacetylase (HDAC) inhibitor, as a single-agent in the treatment of Hodgkin lymphoma (HL) and non- Hodgkin lymphoma (NHL). Data from these studies were presented today at the 49th Annual Meeting and Exposition of the American Society of Hematology (ASH).

MethylGene and Pharmion report preliminary clinical data at the 2007 AACR-NCI-EORTC International Conference

MethylGene Inc. (TSX:MYG) and Pharmion Corporation (NASDAQ:PHRM) today reported preliminary clinical data from the Companies' MGCD0103 Phase I/II combination trial with Gemzar® (Trial 006). The data were presented in a poster session at the 2007 AACR-NCI- EORTC International Conference on Molecular Targets and Cancer Therapeutics in San Francisco on October 24th, 2007.