Optherion's intellectual property was based on genetic discoveries linking certain genes to AMD and orphan renal diseases strongly influenced by components of the alternative complement system. Sequenom is currently marketing a predictive test based on Optherion technology that identifies patients who are predisposed to late stage age-related macular degeneration.

Meanwhile, Baxter, which acquired the rights to Optherion's therapeutic program via an asset purchase and license agreement, is exploring recombinant and plasma-derived complement Factor H as a therapeutic targeting the treatment of AMD.